Author Topic: Practical hint to reassure nice blanks for e.g. LMW kinetics and fragment screen  (Read 983 times)

GE Veronica

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When analyzing small molecules and fragments, poor blanks can ruin the experiment. A practical way to avoid contamination in glass ware that could give rise to unspecific binding in blanks (such as small rests of detergents) is to wash the glassware carefully with 50 mM NaOH followed by MilliQ water before use.

 (If possible, avoid using dishwasher for your glassware when  working with small molecules).

/GE Veronica